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BMP4 monoclonal antibody (26H16)

ADI-905-757-100 100 µg 297.00 USD
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Product Specification

Alternative Name:Bone morphogenetic protein
Immunogen:Recombinant full length human BMP4.
UniProt ID:P12644
Species reactivity:Human
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects bands of ~54kDa, ~42kDa and ~23kDa by Western blot.
Purity Detail:Protein A affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing BSA, 0.09% sodium azide, and 50% glycerol.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Bone morphogenic protein 4 (BMP4) is a member of the TGF-beta superfamily that plays a critical role in mammalian mesenchymal development, influencing hematopoeisis and osteoblast differentiation and function. BMP-4 is secreted as 54 kDa inactive precursor peptides that dimerize and are activated following cleavage by members of the proprotein convertase family. Active BMP-4 binds type I and type II serine/threonine kinase receptors which signal via phosphorylation of Smad family proteins. BMP-4 and the highly homologous BMP-2 are functional orthologues of the decapentaplegic (dpp) gene in Drosophila that regulates embryonic leg and wing imaginal disc patterning and larval gut development.
905-757 WB
Western blot analysis of BMP4. Lane 1, 3: MW, Lane 2: MKN-48, Lane 4: recombinant human BMP4.
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905-757 WB

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