Alternative Name: | Signal transducer and activator of transcription 3 |
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Clone: | 7G8 |
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Host: | Mouse |
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Immunogen: | Recombinant full length human Stat3. |
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UniProt ID: | P40763 |
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Source: | Purified from mouse ascites. |
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Species reactivity: | Human, Mouse, Rat
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Applications: | WB
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Recommended Dilutions/Conditions: | Western Blot (1µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~88kDa by Western blot. |
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Liquid. In PBS, pH 7.2, containing BSA, 0.09% sodium azide, and 50% glycerol. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes. |
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Regulatory Status: | RUO - Research Use Only |
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