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[pSer28]Histone H3 polyclonal antibody

 
ADI-905-752-100 100 µg 260.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human Histone H3 phosphorylated at Ser28.
 
UniProt ID:P68431 (Histone H3.1), Q71DI3 (Histone H3.2), P84243 (Histone H3.2)
 
Species reactivity:Human
 
Crossreactivity:Weakly cross-reacts with mouse, rat, bovine and dog Histone H3.
 
Applications:WB
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The core histones form an octamer, which is made up of one H3-H4 tetramer and two H2A-H2B dimers. The N-terminal tail of core histones undergoes different post-transcriptional modifications including acetylation, phosphorylation, methylation and ubiquitination. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression.
 
905-752 WB
Western blot analysis of Histone H3 (pSer28) using HeLa cell extracts treated with Nocodazole. Lane 1: molecular weight markers, Lane 2: HeLa, Lane 3: HeLa + Nocodazole.
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905-752 WB

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