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PIST polyclonal antibody

 
ADI-905-724-100 100 µg 365.00 USD
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Product Specification

Alternative Name:PDZ protein interacting specifically with TC10
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human PIST.
 
UniProt ID:Q9HD26
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1µg/ml)
Western Blot (1-2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway, is important for normal growth control and may be defective in tumor cells. Golgi-associated PIST (PDZ domain protein interacting specifically with TC10) has been characterized by its ability to bind and regulate the expression of membrane associated proteins. A neural isoform of PIST (nPIST) has been linked to autophagy and neurodegenerative disease by mediating the interaction between the delta2-glutamate receptor and Beclin-1, a Bcl-2-interacting protein homolog of the yeast autophagy gene apg6.
 
PIST polyclonal antibody Western blot
Western blot analysis of PIST in rat colon cell lysate with PIST antibody at (A) 1, (B) 2 and (C) 4µg/ml.
PIST polyclonal antibody Immunohistochemistry
Immunohistochemistry analysis of PIST in rat colon tissue with PIST antibody at 1µg/ml.
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PIST polyclonal antibody Western blot PIST polyclonal antibody Immunohistochemistry

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