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PIST polyclonal antibody

 
ADI-905-724-100 100 µg 347.00 USD
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Product Specification

Alternative Name:PDZ protein interacting specifically with TC10
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human PIST.
 
UniProt ID:Q9HD26
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1µg/ml)
Western Blot (1-2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway, is important for normal growth control and may be defective in tumor cells. Golgi-associated PIST (PDZ domain protein interacting specifically with TC10) has been characterized by its ability to bind and regulate the expression of membrane associated proteins. A neural isoform of PIST (nPIST) has been linked to autophagy and neurodegenerative disease by mediating the interaction between the delta2-glutamate receptor and Beclin-1, a Bcl-2-interacting protein homolog of the yeast autophagy gene apg6.
 
905-724 WB
Western blot analysis of PIST in rat colon cell lysate with PIST antibody at (A) 1, (B) 2 and (C) 4µg/ml.
905-724 IHC
Immunohistochemistry analysis of PIST in rat colon tissue with PIST antibody at 1µg/ml.
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905-724 WB 905-724 IHC

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