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TSC1 polyclonal antibody

 
ADI-905-713-100 100 µg 356.00 USD
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Product Specification

Alternative Name:Hamartin, Tuberous sclerosis 1 protein
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the middle of human TSC1.
 
UniProt ID:Q92574
 
Species reactivity:Human, Mouse, Rat
 
Applications:ICC, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (2µg/ml)
Western Blot (1µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 (Hamartin) or TSC2 (Tuberin) tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases mTOR signaling via stimulation of Rheb GTPase activity.
 
905-713 WB
Western blot analysis of TSC1 in EL4 cell lysate with TSC1 antibody at 1µg/ml in the (A) absence and (B) presence of blocking peptide.
905-713 ICC
Immunocytochemistry analysis of TSC1 in EL4 cells with TSC1 antibody at 2µg/ml.
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905-713 WB 905-713 ICC

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