Product Specification
Alternative Name: | Toll-like receptor 2 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to the sequence near the N-terminus of human TLR2. |
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UniProt ID: | O60603 |
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Species reactivity: | Human, Mouse
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Applications: | IHC, WB
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Recommended Dilutions/Conditions: | Immunohistochemistry (2µg/ml) Western Blot (0.5-2.0µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Ion exchange purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | -20°C |
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Scientific Background: | The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands. |
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Western blot analysis of TLR2 in A20 cell lysates with TLR2 antibody at 1µg/ml in the presence (A) and absence (B) of its blocking peptide.
Immunohistochemistry analysis of human spleen cells using TLR2 antibody at 2µg/ml.
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For Research Use Only. Not for use in diagnostic procedures.