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IRAK-1 polyclonal antibody

 
ADI-905-709-100 100 µg 366.00 USD
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Product Specification

Alternative Name:Interleukin-1 receptor-associated kinase 1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human IRAK-1.
 
UniProt ID:P51617
 
Species reactivity:Human, Mouse, Rat
 
Applications:ICC, IP, WB
 
Purity Detail:DEAE purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression.
 
905-709 WB
Western blot analysis of IRAK in THP-1 (THP) and HeLa (HL) whole cell lysates with IRAK antibody at 1:2000 dilution.
905-709 ICC
Immunocytochemistry analysis of IRAK in HeLa cells with IRAK antibody at 10µg/ml.
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905-709 WB 905-709 ICC

Product Literature References

Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways: H.F. Huang, et al.; World J. Gastroenterol. 21, 2937 (2015), Application(s): Western Blotting, Abstract; Full Text

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