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[pTyr15]Cdk1/cdc2 polyclonal antibody

 
ADI-905-704-100 100 µg 291.00 USD
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Product Specification

Alternative Name:Cell division cycle 2, Cyclin-dependent kinase 1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the C-terminus of human cdc2/Cdk1 phosphorylated at Tyr 15.
 
UniProt ID:P06493
 
Species reactivity:Human
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~34kDa by Western blot.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins.
 
905-704 WB
Western blot analysis of cdc2/Cdk1 (pTyr15). Lane 1: MW, Lane 2: HeLa, Lane 3: HeLa + hydroxyurea.
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905-704 WB

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