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PRMT1 polyclonal antibody

 
ADI-905-699-100 100 µg 255.00 USD
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Product Specification

Alternative Name:SKB, PRDM1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human PRMT1.
 
UniProt ID:Q99873
 
Species reactivity:Human
 
Applications:ELISA, IHC, WB
 
Recommended Dilutions/Conditions:ELISA (1:1,000)
Immunohistochemistry (1:50-1:100)
Western Blot (1:100-1:500)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Protein arginine N-methyltransferases (PRMTs) catalyze the transfer of a methyl group from S-adenosylmethionine (AdoMet) to a guanidine nitrogen of arginine. PRMT1 methylates arginine residues in glycine-rich areas of histone H4 as well as many non-histone substrates that regulate transcriptional activation, mRNA processing, and signal transduction. In contrast, PRMT5 methylates arginines in proline-, glycine-, methionine-rich motifs and is known to interact with Jak kinases. PRMT2 inhibits NF-κB-dependent transcription and promotes apoptosis.
 
905-699 WB
Western blot analysis of PRMT1 in whole HL60 cell.
905-699 IHC
Immunohistochemistry analysis of formalin-fixed and paraffin-embedded human breast carcinoma tissue stained with PRMT1 pAb.
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905-699 WB 905-699 IHC

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