Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

PRMT5 polyclonal antibody

 
ADI-905-698-100 100 µg 265.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:SKB1, PRDM5, HRMT1L5, IBP72, JBP1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a N-terminal portion of human PRMT5.
 
UniProt ID:O14744 (human), Q8CIG8 (mouse), Q4R5M3 (monkey), A7YW45 (bovine)
 
Species reactivity:Human
 
Crossreactivity:Predicted species reactivity based on epitope sequence homology: bovine, mouse, and monkey.
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:10-1:50)
Western Blot (1:100-1:500)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~73kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Protein arginine N-methyltransferases (PRMTs) catalyze the transfer of a methyl group from S-adenosylmethionine (AdoMet) to a guanidine nitrogen of arginine. PRMT1 methylates arginine residues in glycine-rich areas of histone H4 as well as many non-histone substrates that regulate transcriptional activation, mRNA processing, and signal transduction. In contrast, PRMT5 methylates arginines in proline-, glycine-, methionine-rich motifs and is known to interact with Jak kinases. PRMT2 inhibits NF-κB-dependent transcription and promotes apoptosis.
 
905-698 WB
Western blot analysis of PRMT5 in whole HL60 cell lysates.
ADI-905-698 IHC
Immunohistochemistry analysis of human hepatocarcinoma tissue with PRMT5, pAb. Process included formalin-fixation, paraffin-embedding, and antibody peroxidase-conjugated to the secondary antibody.
Please mouse over
905-698 WB ADI-905-698 IHC

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
PRMT
By biological activity:
PRMT Polyclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Stem Cells
Stem Cells
Download as PDF

Brochures
Epigenetics
Epigenetics
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,