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IRAK-4 polyclonal antibody

 
ADI-905-693-100 100 µg 285.00 USD
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Product Specification

Alternative Name:Interleukin-1 receptor-associated kinase 4
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human IRAK4.
 
UniProt ID:Q9NWZ3
 
Species reactivity:Human
 
Applications:ELISA, IHC, WB
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression.
 
905-693 WB
Western blot analysis of Jurkat cell lysates probed with IRAK4 pAb.
905-693 IHC
Immunohistochemistry analysis of formalin-fixed and paraffin-embedded human breast carcinoma tissue stained with IRAK4 pAb.
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905-693 WB 905-693 IHC

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