Product Specification
| Alternative Name: | Interleukin-1 receptor-associated kinase 4 |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to a portion of human IRAK4. |
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| UniProt ID: | Q9NWZ3 |
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| Species reactivity: | Human
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| Applications: | ELISA, IHC, WB
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| Purity Detail: | Protein G affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.09% sodium azide. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression. |
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Immunohistochemistry analysis of formalin-fixed and paraffin-embedded human breast carcinoma tissue stained with IRAK4 pAb.
Western blot analysis of Jurkat cell lysates probed with IRAK4 pAb.
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For Research Use Only. Not for use in diagnostic procedures.
