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[pSer727]Stat1 monoclonal antibody (12C5)

 
ADI-905-670-100 100 µg 370.00 USD
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Product Specification

Alternative Name:Signal transducer and activator of transcription 1
 
Clone:12C5
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to a portion of Stat1 phosphorylated at Ser727.
 
UniProt ID:P42224
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Recommended Dilutions/Conditions:ELISA (0.05µg/ml)
Western Blot (0.5µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~92kDa by Western blot.
 
Purity Detail:Thiophilic adsorption and size exclusion chromatography purified.
 
Formulation:Liquid. In PBS containing 50% glycerol, PEG, sucrose, and 0.09% sodium azide.
 
Use/Stability:Stable at -20°C up to 1 year.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes.
 
905-670 WB
Western blot analysis of untreated (1), EGF stimulated (2), or pervanadate treated (3) A549 cell lysates with Stat1 (pSer727) mAb, clone 12C5.
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905-670 WB

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