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MEK1 monoclonal antibody (3D9)

 
ADI-905-635-100 100 µg 258.00 USD
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Product Specification

Alternative Name:MKK1, MAP kinase kinase 1
 
Clone:3D9
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Native MEK and recombinant MEK1.
 
Species reactivity:Human
 
Applications:ELISA, IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~45kDa (or ~71kDa with GST tag) by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.1% sodium azide. Concentration 1mg/ml.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.
 
905-635 WB
Western blot analysis of MEK1: Lane 1: MW marker, Lane 2: GST-tagged recombinant MEK1
905-635 IHC
Immunohistochemistry analysis of brain tissue stained with anti-MEK clone 3D9.
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905-635 WB 905-635 IHC

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