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Cytochrome c monoclonal antibody (2B5.F8)

 
ADI-905-631-100 100 µg 269.00 USD
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Product Specification

Alternative Name:Cyt c
 
Clone:2B5.F8
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Native horse Cytochrome c.
 
UniProt ID:P00004
 
Species reactivity:Human
Bovine, Dog, Horse
 
Applications:ELISA, IP
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In sodium phosphate containing 0.1% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Cytochrome c, which is a critical component of the electron transport chain, is a component of the functional apoptosome. Upon release from the mitochondria, cytochrome c binds to the adaptor proteins Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex. This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death.
 

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