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Cytochrome c monoclonal antibody (2B5.F8)

ADI-905-631-100 100 µg 274.00 USD
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Product Specification

Alternative Name:Cyt c
Immunogen:Native horse Cytochrome c.
UniProt ID:P00004
Species reactivity:Human
Bovine, Dog, Horse
Applications:ELISA, IP
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In sodium phosphate containing 0.1% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Cytochrome c, which is a critical component of the electron transport chain, is a component of the functional apoptosome. Upon release from the mitochondria, cytochrome c binds to the adaptor proteins Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex. This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death.

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