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Anthrax Lethal Factor monoclonal antibody (LF8)

 
ADI-905-620-100 100 µg 226.00 USD
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Product Specification

Alternative Name:LF, ALF
 
Clone:LF8
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Anthrax lethal factor.
 
UniProt ID:P15917
 
Species reactivity:Bacillus anthracis
 
Applications:ELISA, IP, WB
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.01% sodium azide. Concentration 1mg/ml.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Anthrax Lethal Factor (LF) is a zinc-dependent protease that cleaves mitogen-activated protein kinase kinase (MAPKK) and causes lysis of macrophages. LF, together with Protective Antigen, forms Lethal Toxin, which is the dominant virulence factor produced by B. anthracis and is the major cause of death in infected animals. Lethal toxin has been reported to trigger apoptosis in human melanoma cells.
 

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