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PSCA polyclonal antibody

 
ADI-905-534-1 1 ml 343.00 USD
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Product Specification

Alternative Name:prostate stem cell antigen
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the extracellular region of human PSCA.
 
UniProt ID:O43653
 
Gene/Protein Identifier:8000 (Entrez GeneID)
 
Species reactivity:Human
 
Applications:IHC
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:75)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In PBS, pH 7.4, containing BSA and sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:PSCA (prostate stem cell antigen) is a cell surface antigen overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic cancers. Antibodies directed against PSCA inhibit tumorigenesis, slow tumor growth, prolong survival, and prevent metastasis in a preclinical xenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
 
905-534 IHC
Immunohistochemistry analysis of human breast tissue stained with PSCA antibody.
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905-534 IHC

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