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Phospho-Ser/Thr/Tyr monoclonal antibody (SPM101)

 
ADI-905-522-1 1 ml 345.00 USD
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Product Specification

Alternative Name:Phosphoserine, phosphothreonine, phosphotyrosine
 
Clone:SPM101
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Phosphoserine, phosphotyrosine, and phosphothreonine conjugated to protein carriers.
 
Species reactivity:Species independent
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Western Blot (1:50)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In PBS, pH 7.6, containing 1% BSA and 0.1% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Phosphorylation and dephosphorylation of cellular proteins are central steps in transducing extracellular signals to the cell nucleus. Phosphorylated epitopes may serve as docking sites for the assembly of protein complexes, or may alter the 3-dimensional protein structure, thereby modulating enzymatic activity or the ability to undergo protein-protein-interactions. Modification of proteins on serine residues is mediated by serine/threonine kinases.
 
905-522 IHC
Immunohistochemistry analysis of human breast cancer stained with Phospho-Ser/Thr/Tyr mAb.
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905-522 IHC

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