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PGP9.5 polyclonal antibody

 
ADI-905-520-1 1 ml 334.00 USD
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Product Specification

Alternative Name:Protein gene product, UCH-L1
 
Host:Rabbit
 
Immunogen:Recombinant full length human PGP9.5 (protein gene product 9.5).
 
UniProt ID:P09936
 
Gene/Protein Identifier:7345 (Entrez GeneID)
 
Species reactivity:Human
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:200)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In PBS, pH 7.4, containing BSA and sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Protein gene product (PGP9.5), also known as ubiquitin carboxyl-terminal esterase L1 (UCHL1), is a neuron specific protein structurally and immunologically distinct from neuron specific enolase. The protein, that has a molecular weight of 27kDa, was first identified by high resolution two dimensional PAGE. Standard immunohistochemical techniques have demonstrated the presence of PGP9.5 in neurons and nerve fibres at all levels of the central and peripheral nervous system, in many neuroendocrine cells, in segments of the renal tubules, in spermatogonia and Leydig cells of the testis, in ova and in some cells of both the pregnant and non-pregnant corpus luteum. This antibody is of value as a marker for neurons and may be of particular use in the study of ubiquitinated cellular inclusions characteristic of several chronic human neurodegenerative diseases.
 
905-520 IHC
Immunohistochemistry analysis of human pancreas stained using PGP9.5, pAb.
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905-520 IHC

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