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Oct-2 polyclonal antibody

ADI-905-498-1 1 ml 350.00 USD
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Product Specification

Alternative Name:POU2F2, POU domain class 2 transcription factor 2, OTF2, Octamer-binding protein 2
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human Oct-2. Immunogen shares 100% homology with human Oct-2 isoforms 1, 2, 3 and 5; 50% with human isoform 4; 33% with mouse Oct-2; 46% with rat Oct-2.
UniProt ID:P09086
Gene/Protein Identifier:5452 (Entrez GeneID)
Species reactivity:Human, Mouse, Rat
Recommended Dilutions/Conditions:Immunohistochemistry (1:50)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~50kDa by Western blot.
Purity Detail:Affinity purified.
Formulation:Liquid. In PBS, pH 7.4, containing BSA and sodium azide.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Scientific Background:The POU proteins Oct-1 and Oct-2 were identified as protein activities that selectively interact with octamer DNA sequences that regulate immunoglobulin transcription. The DNA-binding domains of Oct-1 and Oct-2 are highly homologous, and both proteins bind octamer DNA with equal affinity in vitro. Oct-1 is widely expressed whereas Oct-2 expression is restricted to the lymphoid and neuronal compartments.
905-498 IHC
Immunohistochemistry analysis of human tonsil stained with Oct-2, pAb.
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905-498 IHC

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