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GluR1 polyclonal antibody

 
ADI-905-416-1 1 ml 350.00 USD
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Product Specification

Alternative Name:Glutamate receptor 1, AMPA-selective glutamate receptor 1, Glutamate receptor ionontropic AMPA 1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human GluR1.
 
UniProt ID:P42261
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:50)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Affinity purified.
 
Formulation:Liquid. In 10mM PBS, pH 7.4, containing BSA and sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Glutamate receptors constitute the principal excitatory neurotransmitter receptors in the brain. Two classes of Glutamate receptors exist: inotropic receptors and Metabotropic receptors. Inotropic glutamate receptors are oligomeric complexes which are ligandgated calcium channels. Metabotropic glutamate receptors, on the otherhand, are G-protein coupled receptors (GPCRs), which when activated can activate phospholipases or adenylylcyclase, depending on the neuron.
 
905-416 IHC
Immunohistochemistry analysis of human brain stained with anti-GluR1 antibody
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905-416 IHC

Product Literature References

Role of Site-Specific N-Glycans Expressed on GluA2 in the Regulation of Cell Surface Expression of AMPA-Type Glutamate Receptors: Y. Takeuchi, et al.; PLoS One 10, e0135644 (2015), Application(s): Immunoblotting, Abstract; Full Text

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