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BCMA polyclonal antibody

 
ADI-905-306-100 100 µg 366.00 USD
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Product Specification

Alternative Name:B cell maturation protein, TNFRSF 17, CD269
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human BCMA.
 
UniProt ID:Q02223
 
Species reactivity:Human
 
Applications:ELISA, IF, IHC (PS), WB
 
Recommended Dilutions/Conditions:Immunofluorescence (20µg/ml)
Immunohistochemistry (paraffin sections, 10µg/ml)
Western Blot (2-5µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~25kDa by Western blot.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable at -20°C up to 1 year, at 4°C up to 3 months.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:-20°C
 
Scientific Background:Members of the TNF superfamily regulate immune responses and induce apoptosis. Two members of this family were identified and designated BAFF and April, respectively. Three receptors for BAFF were identified; these include: BCMA (B-cell maturation protein), TACI, and BAFF-R. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B-Cell development and survival, activate NF-κB and c-jun N-terminal kinase, and are involved in B-Cell associated autoimmune diseases.
 
ADI-905-306 IF
Immunofluorescence of BCMA in human spleen cells with BCMA antibody at 10µg/ml.
ADI-905-306 WB
Western blot analysis of BCMA in human spleen (A) tissue lysate, K562 (B), and U937 (C) cell lysates with BCMA antibody at 5µg/ml.
ADI-905-306 IHC
Immunohistochemistry analysis of BCMA in human spleen cells with BCMA antibody at 10µg/ml.
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ADI-905-306 IF ADI-905-306 WB ADI-905-306 IHC

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