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p53 DINP1 SIP polyclonal antibody

ADI-905-300-100 100 µg 374.00 USD
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Product Specification

Alternative Name:TRP53, Tumor protein p53
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of human p53DINP1. The is completely conserved between α and β isoforms.
UniProt ID:Q96A56
Species reactivity:Human, Mouse, Rat
Applications:IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (2µg/ml)
Western Blot (1-2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~27kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Scientific Background:p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to Mdm2, SV40 T antigen and human Papilloma virus E6 protein. p53 senses DNA damage and facilitates its repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovary, bladder, colon, lung, and melanoma.
905-300 WB
Western blot analysis of p53DINP1 expression in human lung tissue lysate with p53DINP1 antibody at (A) 0.5 and (B) 1µg/ml.
905-300 IHC
Immunohistochemistry analysis of mouse liver using p53DINP1 antibody at 2µg/ml.
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905-300 WB 905-300 IHC

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