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CCR5 (NT) polyclonal antibody

 
ADI-905-277-100 100 µg 340.00 USD
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Product Specification

Alternative Name:C-C chemokine receptor 5, CD195
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of human CCR5.
 
UniProt ID:P51681
 
Species reactivity:Human
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (20µg/ml)
Western Blot (1:1,000-1:2,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~40kDa by Western blot.
 
Purity Detail:DEAE purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Human immunodeficiency virus (HIV) requires co-receptors, in addition to CD4, to infect target cells. Some G protein coupled receptors such as CCR5, CCR4, CCR3, CCR2b, and CCR8 have been identified as HIV co-receptors. Among them, CCR5 (CCCKR-5) is a principal co-receptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV binding sites.
 
905-277 WB
Western blot analysis of CCR5 in THP-1 whole cell lysate with CCR5 antibody at 1:1000 dilution.
905-277 IHC
Immunohistochemistry analysis of CCR5 in human lymph node tissue with CCR5 antibody at 20µg/ml.
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905-277 WB 905-277 IHC

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For Research Use Only. Not for use in diagnostic procedures.
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