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CCR5 (NT) polyclonal antibody

 
ADI-905-277-100 100 µg 340.00 USD
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Product Specification

Alternative Name:C-C chemokine receptor 5, CD195
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of human CCR5.
 
UniProt ID:P51681
 
Species reactivity:Human
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (20µg/ml)
Western Blot (1:1,000-1:2,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~40kDa by Western blot.
 
Purity Detail:DEAE purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Human immunodeficiency virus (HIV) requires co-receptors, in addition to CD4, to infect target cells. Some G protein coupled receptors such as CCR5, CCR4, CCR3, CCR2b, and CCR8 have been identified as HIV co-receptors. Among them, CCR5 (CCCKR-5) is a principal co-receptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV binding sites.
 
CCR5 (NT) polyclonal antibody Immunohistochemistry
Immunohistochemistry analysis of CCR5 in human lymph node tissue with CCR5 antibody at 20µg/ml.
CCR5 (NT) polyclonal antibody Western blot
Western blot analysis of CCR5 in THP-1 whole cell lysate with CCR5 antibody at 1:1000 dilution.
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CCR5 (NT) polyclonal antibody Immunohistochemistry CCR5 (NT) polyclonal antibody Western blot

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For Research Use Only. Not for use in diagnostic procedures.
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