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PHAP (NT) polyclonal antibody

 
ADI-905-233-100 100 µg 356.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of human PHAP.
 
UniProt ID:P39687
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Western Blot (0.5-2.0µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~28kDa by Western blot.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were identified as important regulators of mitochondrial mediated apoptosis. PHAP appears to facilitate apoptosome mediated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both ras- and myc mediated cell transformation.
 
905-233 WB
Western blot analysis of PHAP expression in human Raji cell lysate with PHAP antibody at 1µg/ml. The wide and strong band below PHAP III is a doublet composed of PHAP I (upper) and PHAP I2a (lower).
905-233 ICC
Immunocytochemistry analysis of PHAP in Raji cells with PHAP antibody at 1µg/ml.
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905-233 WB 905-233 ICC

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