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FLIP γ/δ (CT) polyclonal antibody

 
ADI-905-226-100 100 µg 356.00 USD
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Product Specification

Alternative Name:CASPER, CLARP, I-FLICE, Usurpin
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human FLIPδ/FLIP short form.
 
UniProt ID:O15519
 
Species reactivity:Human
 
Applications:ICC, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (2µg/ml)
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects bands of ~35kDa and ~25kDa by Western blot.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:The cellular FLICE-like inhibitory protein, cFLIP, is a cellular homologue of the viral protein, vFLIP. cFLIP contains two death effector domains (DEDs) and is expressed as either a short or long splice variant called cFLIPs and cFLIPL, respectively. cFLIP acts as a caspase-8 dominant negative regulator, blocking apoptosis induced by the oligimerization of the adapter protein, FADD. cFLIP interacts with FADD and caspase-8 through their respective DEDs.
 
905-226 WB
Western blot analysis of FLIP in total cell lysates from HeLa (H), Jurkat (J), THP-1 (T), A431 (A), K562 (K) and NIH3T3 (N) cells with FLIP antibody at 1:1000 dilution.
905-226 ICC
Immunocytochemistry analysis of HeLa cells using FLIP antibody at 2µg/ml.
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905-226 WB 905-226 ICC

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