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EndoG polyclonal antibody

 
ADI-905-220-100 100 µg 356.00 USD
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Product Specification

Alternative Name:Endonuclease G
 
Host:Rabbit
 
Isotype:IgG
 
Immunogen:Synthetic peptide corresponding to 15 amino acids near the N-terminus of human EndoG. The immunogen is located within amino acids 40 - 90 of EndoG.
 
UniProt ID:Q14249
 
Species reactivity:Human, Mouse, Rat
 
Applications:ELISA, IHC, IHC (PS), WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (2.5-15µg/ml)
Western Blot (2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~35kDa by Western blot.
 
Purity Detail:Affinity chromatography purified via peptide column.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. EndoG is a mitochondrion specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis in a caspase independent fashion.
 
905-220 WB
Western blot analysis of EndoG in mouse (M) 3T3 and human (H) HepG2 cell lysates with EndoG antibody at 2µg/ml.
905-220 IHC
Immunohistochemistry analysis of EndoG in human pancreas with EndoG antibody at 15µg/ml.
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905-220 WB 905-220 IHC

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Endonuclease G
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