| ADI-905-220-100 | 100 µg | 471.00 USD |  |
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| Alternative Name: | Endonuclease G |
| Host: | Rabbit |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide corresponding to 15 amino acids near the N-terminus of human EndoG. The immunogen is located within amino acids 40 - 90 of EndoG. |
| UniProt ID: | Q14249 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | ELISA, IHC, IHC (PS), WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (2.5-15µg/ml) Western Blot (2µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~35kDa by Western blot. |
| Purity Detail: | Affinity chromatography purified via peptide column. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Short Term Storage: | +4°C |
| Long Term Storage: | -20°C |
| Scientific Background: | The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. EndoG is a mitochondrion specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis in a caspase independent fashion. |
| Regulatory Status: | RUO - Research Use Only |
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