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CARD-9 polyclonal antibody

 
ADI-905-188-100 100 µg 357.00 USD
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Product Specification

Alternative Name:Caspase recruitment domain-containing protein 9
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 521-536 of human CARD-9.
 
UniProt ID:Q9H257
 
Species reactivity:Human
 
Applications:ICC, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (10µg/ml)
Western Blot (0.5-1.0µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~59kDa by Western blot.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Apoptotic cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD-9 interacts with the CARD activation domain of BCL-10, a pro-apoptotic activator of NF-κB. CARD-9 is thought to act as a scaffold for the assembly of BCL10 signaling complexes associated with the activation of NF-κB.
 
905-188 WB
Western blot analysis of CARD9 expression in human MDA-MB-361 (A) and PC-3 (B) cell lysate with CARD9 antibody at 2.5µg /ml.
905-188 ICC
Immunocytochemistry analysis of CARD9 in K562 cells with CARD9 antibody at 10µg/ml.
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905-188 WB 905-188 ICC

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