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Bnip3L (IN) polyclonal antibody

ADI-905-185-100 100 µg 374.00 USD
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Product Specification

Alternative Name:BCL2/adenovirus E1B 19kDa interacting protein 3-like, NIX
Immunogen:Synthetic peptide corresponding to aa 77-92 of human Bnip3L.
UniProt ID:O60238
Species reactivity:Human
Applications:IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (2µg/ml)
Western Blot (0.5-1.0µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~40kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Bnip3L/Bnip3alpha/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. In particular, Bnip3L interacts with and overcomes the suppression of apoptosis mediated by Bcl-2 and Bcl-xL.
905-185 WB
Western blot analysis of Bnip3L in K562 whole cell lysate in the absence (A), or presence (B) of immunogenic peptide with Bnip3L antibody (IN) at 1µg/ml.
905-185 IHC
Immunohistochemistry analysis of human kidney tissue using Bnip3L antibody at 2µg/ml.
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905-185 WB 905-185 IHC

General Literature References

Role of BNIP3 and NIX in cell death, autophagy, and mitophagy: J. Zhang & P.A. Ney; Cell Death Diff. 16, 939 (2009), Abstract;

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