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Kallikrein-6 monoclonal antibody (E3)

 
ADI-905-1021-0100 100 µg 399.00 USD
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Product Specification

Alternative Name:KLK6, Neurosin, Protease M
 
Clone:E3
 
Host:Mouse
 
Isotype:IgG
 
Immunogen:Recombinant protein corresponding to aa 17-244 of human kallikrein-6 (His-tagged).
 
UniProt ID:Q92876
 
GenBank ID:30582543
 
Gene/Protein Identifier:5653 (Gene ID)
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~27kDa by Western blot.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In 1X PBS, pH 7.4, containing 10% glycerol and 0.05% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins, including KLK6, are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded KLK6 enzyme is regulated by steroid hormones. In tissue culture, KLK6 has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
 

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