Corticosterone EIA kit



ADI-901-097	5x96 wells	1'130.00 USD

The Corticosterone EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 3 hours. Absorbance is read at 405 nm. The Corticosterone EIA kit has low cross-reactivity with related steroids. The broad dynamic range makes this kit ideal for a wide variety of sample matrices from any species.

Product Specification

Sensitivity:	27.0 pg/ml (range 32 - 20,000 pg/ml)

Kit/Set Contains:	DxS Microtiter plate, Conjugate, Antibody, Assay buffer 15 concentrate, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution, Steroid displacement reagent

Application:	For the quantitative determination of Corticosterone in culture supernatants, feces, plasma, serum, and saliva from any species.

Shipping:	SHIPPED ON BLUE ICE

Long Term Storage:	+4°C

Miscellaneous/General:	Corticosterone is a glucocorticoid secreted by the cortex of the adrenal gland. Corticosterone is produced in response to the stimulation of the adrenal cortex by adrenocorticotropic hormone (ACTH) and is the precursor of aldosterone. Corticosterone production has been shown to increase with stress, with elevated corticosterone levels being associated with impairment of long term memory retrieval and following burn injury. In addition to stress levels, corticosterone is believed to play a decisive role in sleep-wake patterns.

Background / Technical Information:	Please click here for the comprehensive product datasheet.

Product Literature References

CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH: A. Slominski, et al. ; Am. J. Physiol. Endocrinol. Metab. 288, E701 (2005), Application(s): EIA using human culture supernatants, Abstract;

Early life immune challenge alters innate immune responses to lipopolysaccharide: implications for host defense as adults: S. Ellis, et al. ; FASEB J. 19, 1519 (2005), Application(s): EIA using rat plasma, Abstract;

Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog: N.R. Mahapatra, et al. ; J. Clin. Invest. 115, 1942 (2005), Application(s): EIA using mouse cell lysates, Abstract;

Stress hormones: a link between maternal condition and sex-biased reproductive investment: O.P. Love, et al. ; Am. Nat. 166, 751 (2005), Application(s): EIA using avian plasma, Abstract;

Streptozotocin induces G(2) arrest in skeletal muscle myoblasts and impairs muscle growth in vivo: T. Hawke, et al. ; Am. J. Physiol., Cell Physiol. 292, C1033 (2007), Application(s): EIA using rat serum, Abstract;

The anorexic effect of alpha-melanocyte-stimulating hormone ismediated by corticotrophin-releasing factor in chicks: T. Tachibana, et al. ; Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 147, 173 (2007), Application(s): EIA using avian plasma, Abstract;

Assessing the effects of a chronic stressor, stocking density, on welfare indicators of juvenile African catfish, Clarias gariepinus Burchell: J. Schrama, et al. ; Appl. Anim. Behav. Sci. 115, 233 (2008), Application(s): EIA using fish plasma, Abstract;

Dietary sodium manipulation during critical periods in development sensitize adult offspring to amphetamines: F. Flynn, et al. ; Am. J. Physiol. Regul. Integr. Comp. Physiol. 295, R899 (2008), Application(s): EIA using rat plasma, Abstract;

Lack of adrenomedullin in the mouse brain results in behavioral changes, anxiety, and lower survival under stress conditions: A. Martinez, et al. ; PNAS 105, 12581 (2008), Application(s): EIA using mouse serum, Abstract;

MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult: L. Van, et al. ; J. Neuroinflammation 5, U1 (2008), Application(s): EIA using mouse serum, Abstract;

The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat: L. Desbonnet, et al. ; J. Psychiatr. Res. 43, 164 (2008), Application(s): EIA using rat plasma, Abstract;