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Matriptase (human), ELISA kit

Sensitive, rapid ELISA kit to quantify matriptase, a serine protease and unique cancer biomarker.
 
ADI-900-221-0001 96 wells 599.00 USD
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  • Rapid – results in just 3 hours from up to 40 samples in duplicate
  • Convenient – user-friendly alternative to mass spectrometry
  • Easy-to-use – simple procedure, liquid color-coded reagents and pre-coated plates to reduce error
  • Quantitative – fully quantitative results surpass semi-quantitative Western blot analysis
  • Sensitive – measure as little as 1 ng/ml of matriptase
The Matriptase ELISA kit is a complete, colorimetric, immunometric immunoassay kit for the quantitative determination of matriptase in plasma and serum with results in just 3 hours.
ADI-900-221 std curve
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ADI-900-221 std curve

Product Specification

Alternative Name:TADG-15, ST14
 
Sensitivity:1 ng/ml (range 5-280 ng/ml)
 
Assay Time:~3 hours
 
Applications:ELISA, Colorimetric detection
 
Application Notes:For the quantitative determination of human matriptase in plasma and serum.
 
Species reactivity:Human
 
Crossreactivity:No cross-reactivity with other serine proteases was detected for this assay.
 
Use/Stability:Store all components at +4°C
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Kit/Set Contains:Microtiter Plate, Standards, Calibrators, Antibody-conjugate, Streptavidin-HRP, TMB Reagent, Stop Solution, Wash Buffer Concentrate
 
Scientific Background:The protein encoded by the Matriptase gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion and metastasis.
 
UniProt ID:Q9Y5Y6
 
GenBank ID:6647302
 
Gene/Protein Identifier:6768 (Gene ID)
 

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