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LVV Hemorphin 7 ELISA kit

Most sensitive and rapid LVV Hemorphin 7 kit for neuroscience market.
 
ADI-900-205 96 wells 384.00 USD
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  • Sensitive - reliably measure as little as 6.1pg/ml of LVV Hemorphin 7
  • Rapid - results in just 3 hours from up to 40 samples in duplicate
  • Specific - low cross-reactivity to similar peptides
  • Easy-to-use - liquid color-coded reagents reduce errors
The LVV Hemorphin 7 EIA kit is a colorimetric, competitive immunoassay kit with results in just 3 hours.
900-205 parallelism
900-205 std curve
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900-205 parallelism 900-205 std curve

Product Specification

Sensitivity:6.1 pg/ml (range 9.8 - 10,000 pg/ml)
 
Assay Time:3 hours
 
Applications:ELISA, Colorimetric detection
 
Application Notes:For the quantitative determination of species independent LVV Hemorphin 7 in serum and tissue homogenate samples.
 
Species reactivity:Species independent
 
Crossreactivity:LVV Hemorphin 7 (100%) and <0.003%: Leu-Valorphin-Arg (LVV Hemorphin-6), Valorphin, Angiotensin (1-12), Angiotensin I, Angiotensin (1-9), Angiotensin II, Angiotensin (1-7), Angiotensin A, Angiotensin III, Angiotensin IV
 
Use/Stability:Store all components at +4ºC, except Standard at -20ºC.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Kit/Set Contains:Microtiter Plate, Conjugate, Antibody, Assay Buffer 16, Wash Buffer Concentrate, Standard, TMB Substrate, Stop Solution 2, Streptavidin-HRP
 
Scientific Background:Hemorphins are opioid peptides derived by proteolysis from hemoglobin. Their sequences are identical in several mammalian species including human, sheep and bovine. LVV hemorphin 7 (LVVYPWTQRF) binds strongly to the Angiotensin IV (AT4) receptors in the brain. The AT4 receptor is an integral membrane aminopeptidase also known as IRAP (insulin regulated membrane aminopeptidase). LVV hemorphin 7 and AT4 are not substrates but rather inhibitors of the AT4 (IRAP) receptor. Both promote learning and memory and reverse amnesia in animal models. Elevated serum levels of LVV Hemorphin 7 have also been documented in patients with some forms of breast cancers that are associated with an increased expression of cathespins B and D.
 

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