Serotonin ELISA kit

The Serotonin EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 3 hours.

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Alternative Name:	5HT, 5-hydroxytryptamine

Sensitivity:	0.293 ng/ml (range 0.49 - 500 ng/ml)

Kit/Set Contains:	GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution

Application:	For the quantitative determination of Serotonin in platelets, plasma, serum, and urine from any species.

Use/Stability:	Store all components at +4°; except antibody, standard, conjugate at -20°,

Miscellaneous/General:	Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine found in the central nervous system, gastrointestinal tract, and blood with broad physiological functions in neurotransmission, gastric motility, hemostasis, and cardiovascular integrity. Seven subclasses (5-HT 1-7) of serotonin receptors have been identified, a majority of which are members of the seven transmembrane domain-containing GPCR family, and are the target of several anti-depressant drugs. The 5-HT1 subclass consists of five highly homologous receptors that couple via G(i/o) alpha subunits to inhibit adenylyl cyclase activity. 5-HT1A expression in mammals is strongest in CNS limbic pathways that control emotion, including tissue of the hippocampus, dorsal raph�, and septum.