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Glutathione peroxidase activity kit

 
ADI-900-158 5x96 wells 585.00 USD
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  • Validated in a variety of sample types
  • Fast, accurate assay results in less than 30 minutes
  • Convenient 96 well plate format for higher throughput.
The Glutathione Peroxidase activity kit is a convenient 96-well plate based assay for the higher throughput analysis of glutathione peroxidase activity in a variety of sample matrices in just 30 minutes.

Product Specification

Alternative Name:GPx
 
Applications:Colorimetric detection
Activity assay
 
Application Notes:For the measurement of glutathione peroxidase in cell lysates, plasma, and tissue from any species.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Kit/Set Contains:Microtiter plate, Assay buffer concentrate, Reaction mix, Glutathione reductase, GSSG
 
Scientific Background:Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson's disease.
 

Product Literature References

Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy: R. Tobe, et al.; Cancers (Basel) 7, 2262 (2015), Application(s): GPX activities measured in protein extracts , Abstract; Full Text
Defensive mechanism in cholangiocarcinoma cells against oxidative stress induced by chlorine e6-based photodynamic therapy: H.M. Lee, et al.; Drug Des. Devel. Ther. 8, 1451 (2014), Abstract; Full Text
Ets-1 global gene expression profile reveals associations with metabolism and oxidative stress in ovarian and breast cancers: M.L. Verschoor, et al.; Cancer Metab. 1, 17 (2013), Abstract; Full Text
Involvement of ferritin heavy chain in preventive effect of metformin against doxorubicin-induced cardiotoxicity: M.C. Asensio-Lopez, et al.; Free Radic. Biol. Med. 57, 188 (2013), Abstract;

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