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IL-10 (mouse), ELISA kit

 
ADI-900-148 96 wells 530.00 USD
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  • Ready-to-use - liquid color-coded reagents reduce error
  • Sensitive - detect < 4 pg/ml of IL-10
  • Fast - results in < 3 hours from up to 41 samples in duplicate
  • Ready-to-use reagents and pre-coated plates reduce errors and save your time
The IL-10 (mouse), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 5 hours.
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Product Specification

Alternative Name:Interleukin-10
 
Sensitivity:< 12 pg/ml (range 37 - 3,000 pg/ml)
 
Assay Time:5 hours
 
Applications:ELISA, Colorimetric detection
 
Application Notes:For the quantitative determination of mouse IL-10 in culture supernatants and serum. Cited sample type includes plasma (ref. 1).
 
Species reactivity:Mouse
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Kit/Set Contains:Microtiter plate, SA-HRP concentrate, SA-HRP dilution buffer, Biotinylated antibody, Standard, Standard diluent, Wash buffer concentrate, TMB Substrate, Stop solution
 
Scientific Background:Interleukin-10 (IL-10) was initially identified as the Cytokine Synthesis Inhibitory Factor based on the observation that mouse Th1 cytokine production was suppressed by a Th2-derived factor. IL-10 is a macrophage deactivating factor, acting on macrophage-monocyte accessory cells to produce its inhibitory effects on T cells and natural killer cells. It also regulates growth and/or differentiation of B cells, mast cells, granulocytes, dendritic cells, karatinocytes and endothelial cells. Circulating levels of IL-10 are increased in allergic asthma, systemic sclerosis, a variety of cancers, post-transplantation patients, and in sepsis. The therapeutic potential of IL-10 includes rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and HIV infection.
 
UniProt ID:P18893
 

Product Literature References

CLOCK modulates survival and acute lung injury in mice with polymicrobial sepsis: C.Y. Wang, et al.; Biochem. Biophys. Res. Commun. 478, 935 (2016), Application(s): Measurement of cytokine levels in serum and cell culture medium, Abstract;
Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice: Y. Zhao, et al. ; PLoS ONE 4, e4226 (2009), Application(s): EIA using mouse plasma (ref. 1), Abstract;

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