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IL-1β (rat), ELISA kit

ADI-900-131A 96 wells 615.00 USD
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Replaces Prod. #: ADI-900-131

  • Sensitive - use less precious sample per test
  • Higher throughput - test up to 40 samples in duplicate in less than 4 hours
  • Quantitative - obtain statistically significant results and compare data between multiple experiments
  • Ready-to-use - pre-coated plates save time and reduce errors
The IL-1β (rat), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in < 4 hours.

Product Specification

Alternative Name:Interleukin-1β
Sensitivity:4 pg/mL (range 31.3 - 2,000 pg/mL)
Assay Time:<4 hours
Applications:ELISA, Colorimetric detection
Application Notes:For the quantitative determination of IL-1β in culture supernatants and serum of rat origin.
Species reactivity:Rat
Shipping:Shipped on Blue Ice
Long Term Storage:+4°C
Contents:Microtiter plate, SA-HRP concentrate, SA-HRP dilution buffer, Biotinylated antibody, Standard, Standard diluent, Wash buffer concentrate, TMB Substrate, Stop solution
Scientific Background:The interleukin-1 (IL-1) cytokine family consists of IL-1α, IL-1β, and IL-1Rα (receptor antagonist) which are expressed primarily by endothelial cells and activated macrophages. IL-1α and IL-1β elicit pro-inflammatory cytokine production and cellular activation, and are the primary mediators of hypothalamic regulation that results in fever. IL-1α and IL-1βsignals are transmitted via a dual subunit IL-1 receptor composed of IL-1R1 and the IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP is vital to IL-1 signaling, as it recruits the IL-1 receptor-associated kinase (IRAK) to the receptor complex, initiating NF-κB pathway activation.
Technical Info/Product Notes:Cited samples:
Cytokine ELISAs Cited Samples
UniProt ID:Q63264

Product Literature References

Involvement of the P2X7 receptor in the migration and metastasis of tamoxifen-resistant breast cancer: effects on small extracellular vesicles production: M. Park, et al.; Sci. Rep. 9, 11587 (2019), Abstract; Full Text
Hydrogen sulfide protects against amyloid beta-peptide induced neuronal injury via attenuating inflammatory responses in a rat model: H. Fan, et al.; J. Biomed. Res. 27, 296 (2013), Application(s): ELISA using rat hippocampus, Abstract;

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