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COX-2 (human), ELISA kit

Most sensitive COX-II immunoassay kit commercially available for inflammation research.
 
ADI-900-094 96 wells 746.00 USD
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  • Easy-to-use - ready-to-use liquid color-coded reagents reduce errors
  • Reliable - reproducible results day-after-day and lot-after-lot
  • Fast - results in just 2 hours from up to 39 samples in duplicate
The COX-2 (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 2 hours.
900-094 std curve
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900-094 std curve

Product Specification

Alternative Name:Cyclooxygenase-2, Prostaglandin H synthase 2
 
Sensitivity:0.25 ng/ml (range 1.09 - 70 ng/ml)
 
Assay Time:2 hours
 
Applications:ELISA, Colorimetric detection
 
Application Notes:For the quantitative determination of human COX-2 in cell lysates.
 
Species reactivity:Human
 
Crossreactivity:Human COX-2 (100%), human COX-1 (<0.1%)
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Kit/Set Contains:Microtiter plate, Labeled antibody concentrate, Antibody diluent, Assay buffer, Wash buffer concentrate, Standard, TMB Substrate, Stop solution
 
Scientific Background:Cyclooxygenases-1 and 2 (COX-1 and COX-2) also known as Prostaglandin endoperoxide H synthases-1 and 2 are integral membrane proteins which catalyze the first step of prostaglandin, thromboxane, and prostacyclin production from arachidonic acid. The COX-1 and COX-2 enzymes are important pharmacologically as targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin, ibuprofen and the COX-2 inhibitors. Inhibition of cyclooxygenases with NSAIDs acutely reduces inflammation, pain, and fever.
 
UniProt ID:P35354
 

Product Literature References

Anti-Inflammatory Activity of Haskap Cultivars is Polyphenols-Dependent: H.P. Vasantha Rupasinghe, et al.; Biomolecules 5, 1079 (2015), Application(s): ELISA using human leukemia monocytes , Abstract; Full Text
Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages: S. Sekhon-Loodu, et al.; Int. Immunopharmacol. 25, 199 (2015), Application(s): ELISA, Abstract;

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