Endothelin-1 ELISA kit



ADI-900-020A	96 wells	460.00 USD

Sensitive - quantify as little as 0.41 pg/ml ET-1, letting you read both normal and pathological samples
Flexible - option of overnight or 1 hour primary incubation
Versatile - suitable for a variety of sample matrices
Higher throughput - results from up to 38 samples in duplicate in just 2 hours

The Endothelin-1 EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 2 hours. This ultra-sensitive kit lets you quantify as little as 0.41 pg/mL ET-1 in a variety of biological matrices with the option of overnight or a 1 hour primary incubation.

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Product Specification

Sensitivity:	0.40 pg/ml (range 0.78 - 100 pg/ml)

Kit/Set Contains:	Microtiter plate, Antibody diluent, Antibody concentrate, Assay buffer 17, Wash buffer concentrate, Standard, TMB Substrate, Stop solution 2

Application:	For the quantitative determination of ET-1 in culture supernatants, plasma, and serum of human, mouse, rat, cow, dog, pig, and rabbit origin.

Long Term Storage:	+4°C

Miscellaneous/General:	Endothelins (ET) are isopeptides produced by vascular endothelium that have potent vasoconstrictive activity. The peptides are encoded by three separate genes and processed to yield 39-residue "Big ET" molecules which are further processed to the 21 amino acid sequences designated ET-1, ET-2 and ET-3. ET action is mediated via binding to two receptors, ET_A and ET_B. Activation of ET_A increases vasoconstriction and sodium retention, thereby increasing blood pressure. Activation of ET_B receptors triggers the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells and increases urine production and elimination, thereby lowering blood pressure.